Basically an outside wall perpendicular to floor joists. Most simple ranch style houses have two. Typically the front and the rear of the house. Also most simple homes have a beam down the center of the house supporting the floor joists, with a load bearing wall above supporting the roof trusses. Along this center point wall is also an appropriate place to set a large tank..Look up from below and you will see the layout.
My bed has a weight on the floor at night of over 30 pounds per square inch. Just mentioning this so you can see the PSI of an average bed.
If you place the aquarium appropriately in one of these areas you should not have a problem. If you are really concerned, build a triple 2x8 beam and place it 36 inches out from the foundation or load bearing center beam, wherever you plan to put the tank, and support the beam with appropriate length floor jacks. https://www.google.c...use floor jacks If you do this, it will be bombproof and cost you less than $350